¿Cómo funciona el primer test de antígeno nacional para el dengue?

[{"selector":"#anim-ed2a5c42-842d-4926-a191-cb6d8a06413b","keyframes":{"opacity":[0,1]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-84b59bc5-9a15-4fcb-ac43-a48e2be8860a","keyframes":{"transform":["translate3d(0px, -151.08454%, 0)","translate3d(0px, 0px, 0)"]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6c622a8e-6322-436c-adec-f8ca9ebfb59e","keyframes":{"opacity":[0,1]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b237edd6-fb6f-4625-a6c5-ef3d1b903cdb","keyframes":{"transform":["translate3d(0px, 93.06441%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-458d0415-2c6d-4698-80f9-9bcd8ab88e80","keyframes":{"transform":["translate3d(-97.39131%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .8, 1)","fill":"both"}] [{"selector":"#anim-696e104a-d77f-418c-867e-7ce08f4a2e3c","keyframes":{"transform":["rotateZ(-180deg)","rotateZ(0deg)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .5, 1)","fill":"forwards"}] En respuesta a la alarma temporada 2023-2024, que registró el mayor brote de dengue en Argentina con 583.297 casos y 419 muertes, la Administración Nacional de Medicamentos, Alimentos y Tecnología Médica (ANMAT) aprobó el primer test de antígeno de fabricación nacional, el Detect-AR Dengue .

Fue desarrollado en el Laboratorio de Virología Molecular de la Fundación Instituto Leloir, bajo la dirección de la investigadora del CONICET Andrea Gamarnik.

[{"selector":"#anim-330036de-6586-403e-b1c3-5e46cc46ff34","keyframes":{"opacity":[0,1]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-fd056e1d-2c7f-43c1-8a3d-cbf34694eb60","keyframes":{"transform":["translate3d(0px, -364.53229%, 0)","translate3d(0px, 0px, 0)"]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-0465c9c7-7f61-42bb-9358-84d56f69a3d2","keyframes":{"opacity":[0,1]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6d35105c-779c-42a4-94ae-c6f68b7705bb","keyframes":{"transform":["translate3d(0px, 192.37607%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e73ccd81-073c-4a98-866d-61d59edc8736","keyframes":{"transform":["translate3d(-299.99997%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .8, 1)","fill":"both"}] [{"selector":"#anim-1111ac27-e5e2-4954-a529-5163d00f4eda","keyframes":{"transform":["rotateZ(-180deg)","rotateZ(0deg)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .5, 1)","fill":"forwards"}]

Su creación responde a una necesidad específica y urgente del sistema de salud argentino: la detección del antígeno viral NS1, un componente crucial para el diagnóstico temprano del dengue.

[{"selector":"#anim-45a884a2-e45e-4819-9e45-5a50bb489d25","keyframes":{"opacity":[0,1]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3f3df013-2b68-46ab-a99e-5b42e9facedc","keyframes":{"transform":["translate3d(0px, -330.45882%, 0)","translate3d(0px, 0px, 0)"]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a7735c16-3b99-4a49-8b2f-bfd5fbedb0e8","keyframes":{"opacity":[0,1]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-84aec6e4-42a4-42a8-91ee-132c9f53f64a","keyframes":{"transform":["translate3d(0px, 192.37607%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4171c566-f415-4905-9e4f-a2a042069bfd","keyframes":{"transform":["translate3d(-299.99997%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .8, 1)","fill":"both"}] [{"selector":"#anim-f4ad4074-2859-4d51-af14-a2a5ffc8bc65","keyframes":{"transform":["rotateZ(-180deg)","rotateZ(0deg)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .5, 1)","fill":"forwards"}]

El kit permite identificar el virus en aproximadamente tres horas y puede procesar hasta 92 muestras simultáneamente, sin necesidad de equipos especializados.

[{"selector":"#anim-513d7f2a-6c52-47ad-9126-12186df76fbf","keyframes":{"opacity":[0,1]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-0627df3a-9349-496b-91f1-18a384d3bf04","keyframes":{"transform":["translate3d(0px, -169.0521%, 0)","translate3d(0px, 0px, 0)"]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-43a23e04-2562-45a3-9bf8-c0f68e4d9bfa","keyframes":{"opacity":[0,1]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-79a260cf-0733-4edb-bb26-16c097c19e22","keyframes":{"transform":["translate3d(0px, 96.12131%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7561a9b6-730d-4d3b-b50c-1ec821f9eced","keyframes":{"transform":["translate3d(-82.76553%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .8, 1)","fill":"both"}] [{"selector":"#anim-dded37e1-ddda-4886-9fb2-292b5761e877","keyframes":{"transform":["rotateZ(-180deg)","rotateZ(0deg)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .5, 1)","fill":"forwards"}]

Es una alternativa accesible y de menor costo frente a técnicas como la PCR, lo que lo hace más adecuado en situaciones de brotes epidémicos.

[{"selector":"#anim-95d7c3ce-6a71-48b6-89ad-12f94184da59","keyframes":{"opacity":[0,1]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3405e190-1e66-4216-bd16-fe21e95d4f8e","keyframes":{"transform":["translate3d(0px, -405.94978%, 0)","translate3d(0px, 0px, 0)"]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d28f2982-8c85-4a37-9b66-5847f119417a","keyframes":{"opacity":[0,1]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4b96af66-e34e-42d5-8d2e-f612a4c47185","keyframes":{"transform":["translate3d(0px, 179.51644%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1145bea3-f097-4db7-ae6c-dfddd7335247","keyframes":{"transform":["translate3d(-91.26017%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .8, 1)","fill":"both"}] [{"selector":"#anim-9b24daf3-9e3d-4c8d-8444-fa9deff5b6db","keyframes":{"transform":["rotateZ(-180deg)","rotateZ(0deg)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .5, 1)","fill":"forwards"}]

La aprobación del test fortalece la capacidad de respuesta sanitaria en Argentina, disminuyendo la dependencia de insumos importados y mejorando el control de brotes de dengue.

[{"selector":"#anim-8b0c77a2-5881-4c95-88d1-3a660e2836ae","keyframes":{"opacity":[0,1]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5614d6ef-33b5-4cd6-86d3-1a3b431af66f","keyframes":{"transform":["translate3d(0px, -167.92214%, 0)","translate3d(0px, 0px, 0)"]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e7dfcf98-fb13-4e47-8f88-d31fdf218f6b","keyframes":{"opacity":[0,1]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8d6ead3b-a385-4d94-91dd-a989242a005a","keyframes":{"transform":["translate3d(0px, 96.12131%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4531cc48-0f60-42d0-87dc-df7f308ccfad","keyframes":{"transform":["translate3d(-301.45983%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .8, 1)","fill":"both"}] [{"selector":"#anim-4f4848cb-2cf4-4b73-a051-8570dfc99b8f","keyframes":{"transform":["rotateZ(-180deg)","rotateZ(0deg)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .5, 1)","fill":"forwards"}]

[{"selector":"#anim-12909adc-039e-447c-9c07-603a2f431433","keyframes":{"opacity":[0,1]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b87c0bd8-7e04-474a-93fd-b0c7f779f906","keyframes":{"transform":["translate3d(0px, -143.13271%, 0)","translate3d(0px, 0px, 0)"]},"delay":500,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a95def2f-d5fe-482e-8563-8c0042cb1c9b","keyframes":{"opacity":[0,1]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-be8f51f3-9902-47cc-bc61-015d2fac9b67","keyframes":{"transform":["translate3d(0px, 96.58119%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2592013f-b4f1-4f44-9a77-0df49bc67176","keyframes":{"transform":["translate3d(-94.16058%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .8, 1)","fill":"both"}] [{"selector":"#anim-7a2e9d07-cc36-4e1d-9deb-77202aecc20c","keyframes":{"transform":["rotateZ(-180deg)","rotateZ(0deg)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(.2, 0, .5, 1)","fill":"forwards"}] El desarrollo del Detect-AR Dengue fue posible gracias a una colaboración entre diversas instituciones: CONICET , Fundación Instituto Leloir , INIS y Laboratorio Lemos . Se producirán inicialmente 500 unidades del test para evaluar su aceptación en el ámbito clínico, con la posibilidad de aumentar la producción y exportar en el futuro.

[{"selector":"#anim-5c50381f-0f08-4267-8643-f12f6efef66d","keyframes":{"opacity":[0,1]},"delay":2700,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-9dbc7c58-451e-4579-89f9-19c663fbcaca","keyframes":{"transform":["translate3d(0px, -1273.5042%, 0)","translate3d(0px, 0px, 0)"]},"delay":2700,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5e6efa7c-f61a-408a-99f2-45689dcde7d8","keyframes":{"opacity":[0,1]},"delay":1700,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f0022b72-b966-4609-bff9-3b4ca529af0d","keyframes":{"transform":["translate3d(0px, -1299.40869%, 0)","translate3d(0px, 0px, 0)"]},"delay":1700,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-de502c34-0d92-478d-be5c-03e89147fd51","keyframes":{"opacity":[0,1]},"delay":700,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6bbdef0c-0551-4704-b756-545fcd51e5d9","keyframes":{"transform":["translate3d(0px, -1063.62708%, 0)","translate3d(0px, 0px, 0)"]},"delay":700,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}]